Mast cell stabilization + leukotriene axis

immune_innate · immune-hematologic · respiratory

Mast cell stabilization + leukotriene axis. Innate immunity pathway. Mast cells release preformed (histamine, tryptase, heparin) + newly synthesized (LTC4, LTD4…

Modulators

• cromolyn — inhibitor
• zileuton — inhibitor
• zafirlukast — inhibitor
• apremilast — inhibitor
• roflumilast — inhibitor

Sources: PMID:17978293