mTOR signaling

signaling · endocrine · immune-hematologic · musculoskeletal

mTOR signaling. mTORC1 + mTORC2. Signaling pathway. Master regulator of cellular growth, autophagy, and protein synthesis. mTORC1 (raptor-containing) responds to…

Modulators

• rapamycin — inhibitor
• everolimus — inhibitor
• temsirolimus — inhibitor
• tacrolimus — inhibitor
• cyclosporine — inhibitor

Sources: PMID:28283069, PMID:22500797