Pulmonary arterial hypertension

disease_cascade · respiratory · cardiovascular

Pulmonary arterial hypertension. vasodilator axes. Disease cascade pathway. PAH is progressive pulmonary vascular remodeling + vasoconstriction → ↑pulmonary vascular…

Modulators

• sildenafil — inhibitor
• tadalafil — inhibitor
• riociguat — activator
• macitentan — inhibitor
• bosentan — inhibitor