Voltage-gated sodium channels (Nav1.x)

membrane · nervous

Voltage-gated sodium channels (Nav1.x). anticonvulsants + local anesthetics. Membrane pathway. Nav1.x voltage-gated Na+ channels generate the action-potential…

Modulators

• phenytoin — inhibitor
• carbamazepine — inhibitor
• oxcarbazepine — inhibitor
• eslicarbazepine — inhibitor
• lacosamide — inhibitor
• lamotrigine — inhibitor
• zonisamide — inhibitor
• lidocaine — inhibitor
• bupivacaine — inhibitor
• ropivacaine — inhibitor

Sources: PMID:33199904