PEAK ATP

nucleotide · immune-hematologic · Oral

PEAK ATP, a nucleotide. Oral ATP does not enter cells intact — rapidly dephosphorylated in the gut and circulation to ADP → AMP → adenosine → inosine. Proposed…

Oral ATP does not enter cells intact — rapidly dephosphorylated in the gut and circulation to ADP → AMP → adenosine → inosine. Proposed mechanism for ergogenic effects is extracellular ATP signalling at P2X/P2Y purinergic receptors on vascular and immune cells, increasing blood flow and reducing fatigue. Human RCTs show modest power-output improvements.

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