Testosterone Cypionate

hormone · endocrine · Intramuscular

Testosterone Cypionate, a hormone. Androgen receptor agonist; aromatized to estradiol. Intramuscular half-life 8 d.

Androgen receptor agonist; aromatized to estradiol.

Prescription only. TRT context. IM depot models slow first-order absorption (ka ≈ 0.04/hr) into a two-compartment system: distribution α ≈ 0.05/hr (~14h), terminal β ≈ 0.0036/hr (~190h half-life). Replaces the v0.5 1-comp slow-ka approximation. AR receptor-occupancy row removed (2026-06-28 audit): its ~1 nM value was free-testosterone’s affinity cited to a guideline with no verbatim Ki; steroid AR Kd/Ki have no abstract-verbatim source per AUTHORING_GAPS.

Pharmacokinetics

• Intramuscular — t½ 8.0 d · F 100% · ka 0.04 h⁻¹

Related compounds

• Testosterone enanthate — synergistic
• Gonadorelin — synergistic
• Anastrozole — synergistic
• Finasteride — synergistic

Sources: PMID:20525905, PMID:29367424