Uridine

nucleoside · nervous · Oral · Sublingual

Uridine, a nucleoside. Pyrimidine nucleoside — salvaged by uridine-cytidine kinase (UCK1/2) to UMP, then UDP / UTP. Crosses BBB via ENT1/2. Incorporated into…

Pyrimidine nucleoside — salvaged by uridine-cytidine kinase (UCK1/2) to UMP, then UDP / UTP. Crosses BBB via ENT1/2. Incorporated into phosphatidylcholine and phosphatidylethanolamine via the Kennedy pathway; proposed membrane-phospholipid-turnover mechanism behind mood / cognitive effects in small RCTs. Often stacked with DHA + choline ('MIND' formulation in Alzheimer's research).

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