Apoptosis (intrinsic + extrinsic)

cell_death · immune-hematologic · reproductive

Apoptosis (intrinsic + extrinsic). Bcl-2 family. Cell death pathway. Programmed cell death. Intrinsic (mitochondrial) pathway: pro-apoptotic BH3-only proteins (BIM…

Modulators

• venetoclax — inhibitor
• navitoclax — inhibitor
• withaferin-a — activator
• ginsenoside-rg3 — activator

Sources: PMID:23291630, PMID:27178240, PMID:24355989