cAMP / PKA second-messenger signaling

signaling · cardiovascular · endocrine · nervous

cAMP / PKA second-messenger signaling. Signaling pathway. Cyclic AMP is the canonical Gs-coupled second messenger. Adenylate cyclase converts ATP → cAMP on Gs…

Modulators

• caffeine — inhibitor
• theophylline — inhibitor
• theacrine — inhibitor
• cilostazol — inhibitor
• dipyridamole — inhibitor
• pentoxifylline — inhibitor
• apremilast — inhibitor
• roflumilast — inhibitor
• glucagon — activator
• semaglutide — activator

Sources: PMID:23043438, PMID:12209131