CGRP axis

signaling · nervous · cardiovascular

CGRP axis. migraine prophylaxis + acute treatment. Signaling pathway. Calcitonin gene-related peptide (CGRP) is a 37-aa neuropeptide released from trigeminal sensory…

Modulators

• rimegepant — inhibitor
• ubrogepant — inhibitor
• erenumab — inhibitor
• fremanezumab — inhibitor
• galcanezumab — inhibitor
• sumatriptan-succinate — activator

Sources: PMID:26376968