Insulin signaling + glucose homeostasis

signaling · endocrine · cardiovascular

Insulin signaling + glucose homeostasis. Signaling pathway. β-cell insulin secretion + peripheral insulin action set systemic glucose disposal. Insulin → InsR (RTK) →…

Modulators

• insulin — activator
• insulin-glargine — activator
• metformin — inhibitor
• semaglutide — activator
• tirzepatide — activator
• liraglutide — activator
• dulaglutide — activator
• exenatide — activator
• sitagliptin — inhibitor
• saxagliptin — inhibitor

Sources: PMID:3056758, PMID:11742412, PMID:36151309