Mineralocorticoid receptor

receptor_pharmacology · endocrine · cardiovascular · renal

Mineralocorticoid receptor. aldosterone. Receptor pharmacology pathway. The mineralocorticoid receptor (MR, NR3C2) is a steroid nuclear receptor canonically activated…

Modulators

• spironolactone — inhibitor
• eplerenone — inhibitor
• dexamethasone — activator
• cortisol — activator
• cortisol — activator
• prednisone — activator
• prednisolone — activator
• dapagliflozin — inhibitor
• empagliflozin — inhibitor
• canagliflozin — inhibitor

Sources: PMID:30678864, PMID:10639017