NAFLD / MASH

disease_cascade · digestive · endocrine · cardiovascular

NAFLD / MASH. steatohepatitis progression. Disease cascade pathway. Metabolic dysfunction-associated steatotic liver disease (MASLD, renamed from NAFLD in 2023) is…

Modulators

• semaglutide — activator
• tirzepatide — activator
• liraglutide — activator
• dulaglutide — activator
• retatrutide — activator
• pioglitazone — activator
• rosiglitazone — activator
• alpha-tocopherol — inhibitor
• metformin — inhibitor
• empagliflozin — inhibitor

Sources: PMID:38851997, PMID:39609545