FXR / TGR5 bile-acid receptor signaling

receptor_pharmacology · digestive · endocrine

FXR / TGR5 bile-acid receptor signaling. Receptor pharmacology pathway. Bile acids are not just emulsifiers — they are hormones acting through two distinct receptor…

Modulators

• colesevelam — activator
• cholestyramine — activator
• metformin — activator
• semaglutide — activator
• liraglutide — activator
• retatrutide — activator
• tirzepatide — activator
• dulaglutide — activator

Sources: PMID:23395169, PMID:29018272