GnRH pulse generator

endocrine_axis · endocrine · reproductive

GnRH pulse generator. kisspeptin / gonadotrope axis. Endocrine axis pathway. Hypothalamic GnRH neurons fire pulsatile bursts (90-min interpulse interval in adult ♀…

Modulators

• gonadorelin — activator
• leuprolide — inhibitor
• triptorelin — inhibitor
• cetrorelix — inhibitor
• ganirelix — inhibitor
• degarelix — inhibitor
• kisspeptin — activator
• kisspeptin-10 — activator
• hormonal-contraceptives — inhibitor

Sources: PMID:25913220