Methionine

amino-acid · digestive · nervous · Oral

Methionine, an amino acid. Translation-initiator amino acid (every eukaryotic protein starts with Met). Converts to same (S-adenosyl-methionine) — the principal…

Translation-initiator amino acid (every eukaryotic protein starts with Met). Converts to SAMe (S-adenosyl-methionine) — the principal methyl donor for >100 methyltransferases including DNMT (DNA), HMT (histones), COMT (catecholamines), GNMT (creatine), and PEMT (phosphatidylcholine). Demethylated to S-adenosyl-homocysteine (SAH) → Homocysteine → back to methionine (Methionine cycle B12-dependent methionine synthase) or to Cysteine (transsulfuration).

Related compounds

• SAMe — synergistic
• TMG (Betaine) — synergistic
• Homocysteine — caution
• Creatine Monohydrate — synergistic

Sources: PMID:10837313