Serotonin

neurotransmitter · nervous · cardiovascular · digestive · Oral

Serotonin, a neurotransmitter. Synthesised from 5 htp (see serotonin melatonin axis) (AADC) in enterochromaffin cells (90% of body serotonin) and raphe nuclei (CNS…

Synthesised from 5-HTP (see Tryptophan → serotonin → melatonin) (AADC) in enterochromaffin cells (90% of body serotonin) and raphe nuclei (CNS pool). Acts at 14 receptor subtypes across the Serotonin receptor pharmacology 5-HT1–7 families — all GPCRs except 5-HT3 (ligand-gated ion channel). Mood, sleep, nausea, GI motility, vasoconstriction.

Related compounds

• 5-HTP — synergistic
• Tryptophan — synergistic