Tryptophan → serotonin → melatonin

biosynthesis · nervous · endocrine

Tryptophan → serotonin → melatonin. Biosynthesis pathway. Tryptophan is the obligatory precursor for both serotonin (5-HT) and melatonin. Tryptophan hydroxylase (TPH)…

Modulators

• 5-htp — substrate
• tryptophan — substrate
• melatonin — substrate
• ramelteon — activator
• tasimelteon — activator
• tryptophan — substrate
• serotonin — substrate

Sources: PMID:14411077, PMID:14409458, PMID:14171622