Hippo / YAP-TAZ signaling

signaling · musculoskeletal · cardiovascular · digestive · integumentary

Hippo / YAP-TAZ signaling. Signaling pathway. Hippo is the master organ-size control pathway — discovered in Drosophila (Warts/Hippo phenotypes — oversized tissues)…

Modulators

• rapamycin — inhibitor
• everolimus — inhibitor
• metformin — inhibitor
• dasatinib — inhibitor
• atorvastatin — inhibitor
• simvastatin — inhibitor
• curcumin — inhibitor
• resveratrol — inhibitor
• quercetin — inhibitor

Sources: PMID:30566373, PMID:32555376