Progesterone receptor signaling

receptor_pharmacology · reproductive · nervous · endocrine

Progesterone receptor signaling. genomic + non-classical. Receptor pharmacology pathway. The progesterone receptor (PGR, NR3C3) is a steroid nuclear receptor with two…

Modulators

• progesterone — activator
• levonorgestrel — activator
• norethindrone — activator
• drospirenone — activator
• mifepristone — inhibitor
• hormonal-contraceptives — activator
• spironolactone — inhibitor
• finasteride — inhibitor
• dutasteride — inhibitor

Sources: PMID:28651856, PMID:15714387, PMID:29544630