GSH / GSSG redox cycle

signaling · immune-hematologic · cardiovascular · nervous

GSH / GSSG redox cycle. GPx + GR + NADPH. Signaling pathway. Distinct from glutathione_metabolism (synthesis arm: γ-GCS → γ-GC + glycine → GSH) and…

Modulators

• glutathione — substrate
• nac — substrate
• selenium — cofactor
• selenium-methionine — cofactor
• alpha-tocopherol — activator
• astaxanthin — activator
• melatonin — activator
• curcumin — activator
• sulforaphane — activator
• resveratrol — activator

Sources: PMID:23201771