Cellular senescence / SASP / senolytics

cell_death · immune-hematologic · musculoskeletal · cardiovascular · integumentary

Cellular senescence / SASP / senolytics. Cell death pathway. Cellular senescence is a stable cell-cycle arrest triggered by genotoxic stress (replicative telomere…

Modulators

• dasatinib — inhibitor
• quercetin — inhibitor
• fisetin — inhibitor
• navitoclax — inhibitor
• venetoclax — inhibitor
• rapamycin — inhibitor
• everolimus — inhibitor
• metformin — inhibitor
• resveratrol — inhibitor
• curcumin — inhibitor

Sources: PMID:32686219, PMID:28416161