MAPK / ERK (RAS-RAF-MEK-ERK) cascade

signaling · immune-hematologic · nervous · cardiovascular · digestive · reproductive

MAPK / ERK (RAS-RAF-MEK-ERK) cascade. Signaling pathway. The RAS-RAF-MEK-ERK MAP kinase cascade is the canonical RTK → mitogen signaling pathway: RTK ligand binding…

Modulators

• imatinib — inhibitor
• dasatinib — inhibitor
• erlotinib — inhibitor
• sorafenib — inhibitor
• trastuzumab — inhibitor
• curcumin — inhibitor
• resveratrol — inhibitor
• egcg — inhibitor
• quercetin — inhibitor
• luteolin — inhibitor

Sources: PMID:30794926, PMID:33992782