Ferroptosis

cell_death · immune-hematologic · nervous · cardiovascular · renal · digestive

Ferroptosis. GPX4 / lipid peroxidation / iron. Cell death pathway. Ferroptosis is an iron-dependent regulated cell death driven by lethal lipid peroxidation —…

Modulators

• alpha-tocopherol — inhibitor
• tocotrienols — inhibitor
• gamma-tocopherol — inhibitor
• selenium — activator
• coq10 — inhibitor
• idebenone — inhibitor
• glutathione — activator
• dha — substrate
• epa — substrate
• curcumin — inhibitor

Sources: PMID:32413317, PMID:26653790