Kynurenine pathway

catabolism · immune-hematologic · nervous · endocrine

Kynurenine pathway. tryptophan catabolism + immunometabolism. Catabolism pathway. The kynurenine pathway (KP) handles ~95% of dietary tryptophan catabolism — the…

Modulators

• tryptophan — substrate
• 5-htp — inhibitor
• niacin — inhibitor
• pyridoxine — cofactor
• melatonin — inhibitor
• curcumin — inhibitor
• resveratrol — inhibitor
• egcg — inhibitor
• quercetin — inhibitor
• psilocybin — inhibitor

Sources: PMID:26035167